Rare, rarer, rarest: lessons from the largest retrospective study to date on mediastinal sarcomas

Physicians concerned with the diagnosis and management of patients with mediastinal tumors are used to the fact that they have to rely on hardly any secured data and little evidence-based knowledge for their decisions. But even by these standards, primary mediastinal sarcomas are extremely rare tumors that account for no more than 5% of mediastinal neoplasms. Less than 1% of soft tissue sarcomas are located in the mediastinum.